Indiana is not only home to America’s first successful wine production operation, but was also at the heart of America’s largest wine producing region. John Dufour, a Swiss immigrant, started the country’s first successful wine venture in Vevay in 1802, and by the mid 1800’s, the Ohio River Valley was the largest wine producing area in the U.S.Scroll down to find Indiana’s best wineries. The “Highest Visitor Ratings” section lists Indiana wineries that have received visitors’ highest ratings for service, views, and wine quality. The “Highest Wine Critic Ratings” section lists the producers of Indiana’s best wines based on awards won at international wine competitions.The “All Indiana Wineries” section contains a comprehensive, and continuously updated, list of Indiana wineries. Click “map view” to access the advanced winery search to find wineries that provide vineyard lodging, have food available to complement their wines, host vineyard weddings, or produce wines from organic grapes. We make it easy to find the best wine tour and tasting destinations in Indiana wine country.