The Shawnee Hills American Viticultural Area (AVA), established in 2006, is located between the Mississippi River and the Ohio River in southern Illinois. The region’s sandstone and limestone soils and elevated topography help mitigate the negative effects of the area’s significant rainfall and high humidity. Scroll down for a comprehensive list of Shawnee Hills wineries and click “map view” to access the advanced winery search. Whether you would like to visit a winery that provides beautiful vineyard lodging, has food available to complement its wines, or hosts vineyard weddings, we make it easy to find the best Shawnee Hills wine tasting and touring destinations.